Duonase Nasal Spray is indicated to be used for managing symptoms of allergic rhinitis in adults. It has been formulated using azelastine hydrochloride and fluticasone propionate as active compounds with targeted mode of action. This spray is histamine H-1 receptor antagonist which is also known to possess anti-inflammatory & mast-cell stabilizing property. It shows bioavailability of about 40% with elimination half life of about 22 hours. Duonase Nasal Spray has also shown effectiveness for bronchoconstriction, vasodilation, & spasmodic contractions. It is available at highly competitive rates in bulk amounts for our respected clients.